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Created with Fabric.js 1.4.5 Polycystic Kidney Disease Increased pressure on marginal lands, exploitation of water bodies, soils, & air through carbon emissions, pesticides, salination, irrigation, + fertilization The two major forms of polycystic kidney disease are distinguished by the usual age of onset and the pattern in which it is passed through families. The autosomal dominant form (sometimes called ADPKD) has signs and symptoms that typically begin in adulthood, although cysts in the kidney are often present from birth or childhood. Autosomal dominantpolycystic kidney disease can be further dividedinto type 1 and type 2, depending on the genetic cause. Polycystic kidney disease is a fairly common genetic disorder. It affects about 500,000 people in the United States. The autosomal dominant form of the disease is much more common than the autosomal recessive form. Autosomal dominant polycystic kidney disease affects 1 in 500 to 1,000 people, while the autosomal recessive type occurs in an estimated 1 in 20,000 to 40,000 people. TRANSMISSION CAUSES OCCURENCE DESCRIPTION Polycystic kidney disease (PKD) is a genetic disorder characterized by the growth of numerous cysts in the kidneys.Clusters of fluid-filled sacs, called cysts, develop in the kidneys and interfere with their ability to filter waste products from the blood. The growth of cysts causes the kidneys to become enlarged and can lead to kidney failure. UTI, hematuria, liver/pancreatic cysts, high BP, kidney stones, aneurysms, diverticulosis. PKD is an inherited disorder.Therefore, your healthcare provider will probably review your family history. A complete blood count (CBC) looking for anemia or signs of infection and a urinalysis looking for blood and/or protein will be ordered. DIAGNOSIS double click to change this title text! double click to changethis text! Drag a cornerto scale proportionally. TREATMENT/CURES Patients with autosomal dominant polycystickidney disease (ADPKD) who progress to end-stage renal disease may require hemodialysis, peritoneal dialysis, or renal transplantation. A study by Torres et al identified serum high-density lipoprotein (HDL) cholesterol, urine sodium excretion (UNa V), and 24-hour osmolality as having a likely effect on ADPKD progression. Whether modification of these components influences the clinical course of ADPKD remains unclear. If you have polycystic kidney disease and you're considering having children, a genetic counselor can help you assess your risk of passing the disease to your offspring.
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