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Created with Fabric.js 1.4.5 Wilms Tumor Wilms' tumor (nephroblastoma) is a rare kidney cancer in which malignant cells are found in the kidney, and may spread to the lungs, liver, or nearby lymph nodes. It primarily affects children. Wilms' tumor most often occurs in just one kidney, though it can sometimes be found in both kidneys at the same time. double click to change this title text! It is the most common cancer of the kidneys in children and most often affects children ages 3 to 4. Approximately 500 cases are diagnosed in the U.S. annually. The majority (75%) occur in otherwise normal children; a minority (25%) are associated with other developmental abnormalities. It is highly responsive to treatment, with about 90% of patientssurviving at least five years. The exact cause of this tumor in most children is unknown.It is more common among some siblings and twins, which suggests a possible genetic cause. Abdominal pain, Abnormal urine color (blood), Constipation, Fever, General discomfort or uneasiness, High blood pressure, Increased growth on only one side of the body, Loss of appetite,Nausea, Swelling in the abdomen, Vomiting.First sign is normally a painless abdominal tumor that can be easily felt by the doctor. An ultrasound scan, CT scan, or MRI scan is done first. A tumor biopsy is not typically performed dueto the risk of creating fragments of cancer tissue and seeding the abdomen with malignant cells. BUN, CBC, CreatinineCreatinine clearance, Intravenous pyelogram ( X-ray test thatprovides pictures of the kidneys, the bladder, the ureters, andthe urethra), and Urinalysis. No prevention Treatment for Wilms' tumor usually begins with surgery to remove all or part of a kidney (nephrectomy). But treatments may vary by the stage of the cancer and chemotherapy or radiation therapy may be needed if the cancer has spread. Cure is to remove all cancerous cells. Trials being done include genetic studies at NCI to concludewhy some people develop cancers and tumors, why some families have more cancers than others,and whether certain genes or regions of DNA affect a person's risk of getting cancer. Lindsey Selva
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