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Created with Fabric.js 1.4.5 Marfan Syndrome What Causes Marfan Synrome...? The symptoms of Marfan syndrome How to diagnose Marfan Syndrome. What gene or chromosome is affected by this disorder? (X, Y, #21) By: Gwenith. Period 8 science These include: -Long arms, legs and fingers. -Tall and thin body type. -Curved spine. -Chest sinks in or sticks out. -Flexible joints. -Flat feet. -Crowded teeth. -Stretch marks on the skin that are not related to weight gain or loss double click to changethis text! Drag a cornerto scale proportionally. Marfan syndrome is caused by defects in a genecalled fibrillin-1. Fibrillin-1 plays an important role as the building block for connective tissue in the body. -Lung tissue (there may be a pneumothorax, in which air can escape from the lung into the chest cavity and collapse the lung) -The aorta, the main blood vessel that takes blood from the heart to the body may stretch or become weak (called aortic dilation or aortic aneurysm) -The eyes, causing cataracts and other problems (such as a dislocation of the lenses) -The skin -Tissue covering the spinal cord Symptoms of Marfan Syndrome. Although there is no cure for Marfan syndrome, there are several options that can minimize and prevent complications. Individualized Marfan syndrome treatment programs are available -- the specific one the doctor recommends will depend on which body systems have been affected. What population (types of people: boys, girls, older people, babies, certain races, etc.)? Can ANYONE get this disorder or is it limited to a certain typeof people? Estimates indicate about one in 3,000 to 5,000 individuals have Marfan syndrome. Each parent with the condition has a 50% risk of passing the genetic defect on to any child due to its autosomal dominant nature. Most individuals with Marfan syndrome have another affected family member. Anyone can get this disorder, not just a certain type of race, or age. Your doctor will diagnose Marfan syndrome based on your medical and family histories, a physical exam, and test results. He or she also will consult a set of guidelines called Ghent criteria, which are used to diagnose Marfan syndrome.
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