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Created with Fabric.js 1.4.5 Central diabetes insipidus is alack of vasopressin, anantidiuretic hormone,that causes excessiveproduction of diluted urine (polyuria). your artboard start from scratch[clears the canvas] Diabetes Insipidus What is it? Central diabetesinsipidus may be inherited,or it may be caused by:- damage done during surgeryon the hypothalamus orpituitary gland- a brain injury, particularlya fracture of the base of the skull- a tumor- sarcoidosis- tuberculosis- an aneurysm- blockage in the arteries leading tothe brain- encephalitis or meningitis- Langerhans cell histiocytosis Causes Diagnosis Occurrence Signs and symptoms include:-excessive thirst-excessive urine production(polyuria).The person often wakes duringthe night to urinate & may drinkhuge amounts of fluid (3 to 30 litersper day) to make up for the fluid lostin urine. When compensation is notpossible, dehydration can quickly follow, resulting in low blood pressure and shock. 1 in 25,000 people have diabetes insipidus12,756 people have diabetes Insipidus in the United States Clinical Manifestation -Desmopressin (modified form ofvasopressin), which controls urineoutput,maintains fluid balance, andprevents dehydration. It is taken ittwo to three times a day, usually asa nasal spray, tablets, or injections.-Drugs that stimulate production of vasopressin, such as chlorpropamide,carbamazepine, clofibrate, and thiazidediuretics. This is only for mild cases.-In extremely mild cases, the patient may only need to drink more water. Aside from a completemedical history andmedical examination, diagnostic procedures for diabetes insipidus mayinclude:urine testsblood testswater deprivation test (to observe if dehydrationoccurs) Treatment There is no cure fordiabetes insipidus andno way to prevent it.Clinical trials are beingtested only to diagnosediabetes insipidus more efficiently by measuring coeptin in urine and todetermine the modeof inheritance ofdiabetes insipidus. Cure, Clinical Trials,& Prevention
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